Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 5/20 | 0.33 |
| ▸ | ANPEP | P15144 | 2/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10910429 | 0.82 | EPHX1 (0.48) | EPHX1DPP4TP53 | |
| SCHEMBL3667003 | 0.82 | EPHX1 (0.48) | EPHX1DPP4TP53 | |
| SCHEMBL80338 | 0.82 | — | — | |
| SCHEMBL18402782 | 0.82 | EPHX1 (0.48) | EPHX1DPP4TP53 | |
| Ammonia Solution, Strong SCHEMBL2962247 | 0.79 | EPHX1 (0.46) | EPHX1DPP4TP53 | |
| SCHEMBL3668939 | 0.79 | — | — | |
| SCHEMBL4383615 | 0.73 | — | — | |
| Cyclohexylamine SCHEMBL2497018 | 0.70 | CA12 (0.39) | EPHX1CA12CA7CA14CA9 | |
| SCHEMBL11803454 | 0.70 | CA12 (0.41) | EPHX1CA12CA7CA14CA9 | |
| Cyclohexane SCHEMBL5501353 | 0.69 | CA12 (0.36) | CA12CA7CA14CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008154705-A1 | TRANSDERMAL DELIVERY OF ACTIVE AGENTS | APOLLO LIFE SCIENCES LIMITED (AU) | 2008-12-24 | — | — | WO | disclosed |
| EP-1978997-A1 | TRANSDERMAL DELIVERY OF PHARMACEUTICAL AGENTS | Apollo Life Sciences Limited (AU) | 2008-10-15 | — | — | EP | disclosed |
| US-20070243132-A1 | Transdermal delivery of pharmaceutical agents | APOLLO LIFE SCIENCES LIMITED (AU) | 2007-10-18 | — | — | US | disclosed |
| WO-2007070983-A1 | TRANSDERMAL DELIVERY OF PHARMACEUTICAL AGENTS | APOLLO LIFE SCIENCES LIMITED (AU) | 2007-06-28 | — | — | WO | disclosed |