Sugi Predict

Sugi Predict / Compounds / Cyclohexylamine

Cyclohexylamine

Cyclohexylamine

SCHEMBL2497018

N.NC1CCCCC1.O=S(=O)([O-])[O-].[Pt+2]

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Cyclohexylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ CA12 O43570 2/20 0.39
▸ CA7 P43166 2/20 0.39
▸ CA14 Q9ULX7 2/20 0.39
▸ CA9 Q16790 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.38
▸ CA1 P00915 3/20 0.36
▸ CA2 P00918 2/20 0.36
▸ MMP8 P22894 2/20 0.34
▸ MMP1 P03956 1/20 0.34
▸ MMP2 P08253 1/20 0.33
▸ THRB P10828 1/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ EPHX1 P07099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclopentanamine SCHEMBL17102897 0.95 CA12 (0.34) CA12CA7CA14CA9ALDH1A1
Cyclohexylamine SCHEMBL2502617 0.95 CA7 (0.39) CA12CA7CA14CA9ALDH1A1
Cyclopentanamine SCHEMBL11415557 0.95 CA12 (0.37) CA12CA7CA14CA9ALDH1A1
Cyclohexylamine SCHEMBL9550780 0.90 CA12 (0.39) CA12CA7CA14CA9ALDH1A1
Sulfuric Acid SCHEMBL9745258 0.86 CA12 (0.31) CA12CA7CA14CA9
Cyclohexylamine SCHEMBL7357490 0.84 CA7 (0.44) CA12CA7CA14CA9ALDH1A1
Cyclohexylamine SCHEMBL10786807 0.82 ALDH1A1 (0.38) CA12CA7CA14CA9ALDH1A1
Cyclopentanamine SCHEMBL19198717 0.82 CA12 (0.33) CA12CA7CA14CA9CA1
Sulfuric Acid SCHEMBL15710815 0.80 SMYD3 (0.31) —
Cyclohexylamine SCHEMBL29359180 0.80 THRB (0.41) ALDH1A1MMP8MMP1MMP2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8030506-B2 Tumor selective and biodegradable cyclotriphosphazene-platinum(II) conjugate anticancer agent, and preparation method thereof NANOHYBRID CO., LTD (KR) 2011-10-04 — — US disclosed
US-20100249226-A1 TUMOR SELECTIVE AND BIODEGRADABLE CYCLOTRIPHOSPHAZENE-PLATINUM(II) CONJUGATE ANTICANCER AGENT, AND PREPARATION METHOD THEREOF NANOHYBRID CO., LTD (KR) 2010-09-30 — — US disclosed
EP-2137200-A1 TUMOR SELECTIVE AND BIODEGRADABLE CYCLOTRIPHOSPHAZENE-PLATINUM(II) CONJUGATE ANTICANCER AGENT, AND PREPARATION METHOD THEREOF Nanohybrid Co., Ltd. (KR) 2009-12-30 — — EP disclosed
WO-2008130121-A1 TUMOR SELECTIVE AND BIODEGRADABLE CYCLOTRIPHOSPHAZENE-PLATINUM(II) CONJUGATE ANTICANCER AGENT, AND PREPARATION METHOD THEREOF NANOHYBRID CO., LTD. (KR) 2008-10-30 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100249226-A1 TUMOR SELECTIVE AND BIODEGRADABLE CYCLOTRIPHOSPHAZENE-PLATINUM(II) CONJUGATE ANTICANCER AGENT, AND PREPARATION METHOD THEREOF PHOSPHO1, TYMP, PAICS CA12 78/4885CA7 191/4885CA14 71/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.