Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GRN | P28799 | 1/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8108093 | 1.00 | MAPT (0.39) | MAPTNPSR1POLBRECQLALDH1A1 | |
| SCHEMBL1295811 | 0.85 | SMN1; SMN2 (0.42) | NPSR1ALDH1A1SRRLMNA | |
| SCHEMBL1929736 | 0.85 | SMN1; SMN2 (0.42) | NPSR1ALDH1A1SRRLMNA | |
| SCHEMBL5970585 | 0.85 | SMN1; SMN2 (0.42) | NPSR1ALDH1A1SRRLMNA | |
| SCHEMBL5282712 | 0.84 | MAPT (0.39) | MAPTALDH1A1SRR | |
| SCHEMBL6686840 | 0.83 | MAPT (0.37) | MAPTNPSR1POLBRECQLALDH1A1 | |
| SCHEMBL5970973 | 0.82 | PPARG (0.47) | POLBALDH1A1SRR | |
| SCHEMBL31647804 | 0.81 | FOLH1 (0.39) | POLBALDH1A1MAPK1SRR | |
| SCHEMBL17027649 | 0.80 | PPARG (0.43) | MAPTPOLBALDH1A1MAPK1KMT2A | |
| SCHEMBL1927300 | 0.80 | KMT2A (0.41) | MAPK1KMT2ALMNAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008151306-A1 | SYNTHESIS OF CYCLODEPSIPEPTIDE COMPOUNDS HAVING ANTINEOPLASTIC AND/OR ANTIMICROBIAL ACTIVITY | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2008-12-11 | — | — | WO | disclosed |