Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | LAP3 | P28838 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6683815 | 0.85 | ACP3 (0.35) | ANPEPKMT2AMEN1CYP3A4HTT | |
| SCHEMBL8108093 | 0.83 | MAPT (0.39) | MAPTNPSR1POLBRECQLALDH1A1 | |
| SCHEMBL4753942 | 0.83 | MAPT (0.39) | MAPTNPSR1POLBRECQLALDH1A1 | |
| SCHEMBL6686833 | 0.76 | POLB (0.34) | MAPTPOLBMAPK1CYP3A4HTT | |
| SCHEMBL12227372 | 0.73 | POLB (0.37) | POLBALDH1A1KMT2AMEN1CYP3A4 | |
| SCHEMBL5970244 | 0.73 | CETP (0.33) | MAPTPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL1929736 | 0.72 | SMN1; SMN2 (0.42) | NPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1295811 | 0.72 | SMN1; SMN2 (0.42) | NPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5970585 | 0.72 | SMN1; SMN2 (0.42) | NPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9441538 | 0.71 | MAPT (0.35) | MAPTKMT2AMEN1CYP3A4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004072047-A1 | INDOLES, BENZIMIDAZOLES OR NAPHHIMIDAZOLES AS HISTONE DEACETYLASE (HDAC) INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-26 | — | — | WO | disclosed |