Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.58 |
| ▸ | MEN1 | O00255 | 8/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | GBA1 | P04062 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4097314 | 0.91 | KMT2A (0.59) | KMT2AMEN1SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL4089290 | 0.84 | KMT2A (0.58) | KMT2AMEN1SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL4755931 | 0.82 | MEN1 (0.56) | KMT2AMEN1ALDH1A1TSHRGAA | |
| SCHEMBL4753603 | 0.79 | ALDH1A1 (0.43) | KMT2AMEN1SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL4103685 | 0.77 | MEN1 (0.57) | KMT2AMEN1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL4089697 | 0.77 | MEN1 (0.55) | KMT2AMEN1SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL4096171 | 0.74 | MEN1 (0.67) | KMT2AMEN1SMN1; SMN2TSHRPOLB | |
| SCHEMBL4095953 | 0.74 | MEN1 (0.67) | KMT2AMEN1ALDH1A1TSHRGAA | |
| SCHEMBL1084085 | 0.74 | MEN1 (0.67) | KMT2AMEN1ALDH1A1TSHRPOLB | |
| SCHEMBL4095930 | 0.73 | MEN1 (0.66) | KMT2AMEN1SMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157500-A1 | AMINOQUINAZOLINE CANNABINOID RECEPTOR MODULATORS FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |