Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 13/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754052 | 1.00 | REN (0.36) | RENBRD4MEN1KMT2ABACE1 | |
| SCHEMBL4754046 | 1.00 | REN (0.36) | RENBRD4MEN1KMT2ABACE1 | |
| SCHEMBL4756778 | 0.95 | REN (0.37) | REN | |
| SCHEMBL4756444 | 0.95 | REN (0.37) | REN | |
| SCHEMBL4756436 | 0.95 | REN (0.37) | REN | |
| SCHEMBL4756450 | 0.95 | REN (0.37) | REN | |
| SCHEMBL4756773 | 0.95 | REN (0.37) | REN | |
| SCHEMBL3465606 | 0.87 | REN (0.41) | REN | |
| SCHEMBL8224074 | 0.84 | REN (0.36) | REN | |
| SCHEMBL4757244 | 0.80 | REN (0.39) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1911762-A1 | Amino alcohols and their use as renin inhibitors | Speedel Experimenta AG (CH) | 2008-04-16 | — | — | EP | disclosed |