Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14601234 | 1.00 | ALDH1A1 (0.39) | ALDH1A1KMT2AL3MBTL1LMNAMEN1 | |
| Hydrochloric Acid SCHEMBL5577050 | 0.99 | ALDH1A1 (0.38) | ALDH1A1KMT2AL3MBTL1LMNAMEN1 | |
| SCHEMBL5576370 | 0.98 | ALDH1A1 (0.39) | ALDH1A1KMT2AL3MBTL1LMNAMEN1 | |
| SCHEMBL4752280 | 0.98 | ALDH1A1 (0.39) | ALDH1A1KMT2AL3MBTL1LMNAMEN1 | |
| SCHEMBL14601232 | 0.98 | ALDH1A1 (0.39) | ALDH1A1KMT2AL3MBTL1LMNAMEN1 | |
| Hydrochloric Acid SCHEMBL4752275 | 0.97 | ALDH1A1 (0.38) | ALDH1A1KMT2AL3MBTL1LMNAMEN1 | |
| Hydrochloric Acid SCHEMBL4752278 | 0.97 | ALDH1A1 (0.38) | ALDH1A1KMT2AL3MBTL1LMNAMEN1 | |
| Hydrochloric Acid SCHEMBL4859001 | 0.84 | ALDH1A1 (0.35) | ALDH1A1KMT2AL3MBTL1LMNAMEN1 | |
| SCHEMBL924409 | 0.83 | KMT2A (0.45) | ALDH1A1KMT2AL3MBTL1LMNAMEN1 | |
| SCHEMBL3539982 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KMT2AL3MBTL1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1909575-A2 | SUBSTITUTED N-CINNAMYL BENZAMIDES | ChemoCentryx Inc (US) | 2008-04-16 | — | — | EP | disclosed |
| US-20070021484-A1 | Substituted N-cinnamyl benzamides | CHEMOCENTRYX, INC. (US) | 2007-01-25 | — | — | US | disclosed |
| WO-2007002842-A2 | SUBSTITUTED N-CINNAMYL BENZAMIDES | CHEMOCENTRYX, INC. (US) | 2007-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021484-A1 | Substituted N-cinnamyl benzamides | BRDT, BCCIP, NAT10 | ALDH1A1 244/4885KMT2A 413/4885L3MBTL1 1252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.