Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2A | Q92830 | 3/20 | 0.38 |
| ▸ | PLA2G6 | O60733 | 2/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.30 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754340 | 1.00 | KAT2A (0.38) | KAT2APLA2G6PLA2G4ATP53MEN1 | |
| SCHEMBL12660142 | 0.93 | KAT2A (0.35) | KAT2APLA2G6PLA2G4ATP53MEN1 | |
| SCHEMBL8239541 | 0.93 | KAT2A (0.35) | KAT2APLA2G6PLA2G4ATP53MEN1 | |
| SCHEMBL7130234 | 0.87 | PRKCA (0.41) | PLA2G6PLA2G4ATP53MEN1CYP1A2 | |
| SCHEMBL13449682 | 0.87 | KAT2A (0.33) | KAT2A | |
| SCHEMBL127823 | 0.85 | KAT2A (0.34) | KAT2APLA2G6PLA2G4ATP53 | |
| SCHEMBL14981010 | 0.85 | KAT2A (0.34) | KAT2APLA2G6PLA2G4ATP53 | |
| SCHEMBL13449685 | 0.85 | KAT2A (0.34) | KAT2APLA2G6PLA2G4ATP53 | |
| SCHEMBL19769963 | 0.85 | KAT2A (0.32) | KAT2ADAGLA | |
| SCHEMBL31377052 | 0.83 | PRSS1 (0.38) | KAT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008155619-A2 | PREPARATION OF OPTICALLY-ACTIVE CYCLIC AMINO ACIDS | PFIZER INC. (US) | 2008-12-24 | — | — | WO | disclosed |
| EP-1912936-A2 | STEREOSELECTIVE SYNTHESIS OF 3,4-DISUBSTITUTED CYCLOPENTANONES AND RELATED COMPOUNDS | Pharmacia & Upjohn Company LLC (US) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007010387-A2 | STEREOSELECTIVE SYNTHESIS OF 3,4-DISUBSTITUTED CYCLOPENTANONES AND RELATED COMPOUNDS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2007-01-25 | — | — | WO | disclosed |