SCHEMBL475448

SCHEMBL475448

CCCC(C(=O)O)C(C(=O)O)[Si](C)(OCC)OCC

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 0.38
AKR1A1 P14550 1/20 0.38
CHRM3 P20309 1/20 0.38
HTR2A P28223 1/20 0.38
HTR2C P28335 1/20 0.38
ADRA1A P35348 1/20 0.38
HRH1 P35367 1/20 0.38
DRD3 P35462 1/20 0.38
SLC6A3 Q01959 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC2 Q92769 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
GRIK1 P39086 1/20 0.31
SLC1A3 P43003 1/20 0.31
SLC1A2 P43004 1/20 0.31
SLC1A1 P43005 1/20 0.31
GRIK2 Q13002 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL475642 0.84 CHRM1 (0.39) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL475635 0.84 CHRM1 (0.39) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL475440 0.74 CHRM1 (0.40) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL14110749 0.71 TDP1 (0.60) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL5031485 0.71 TDP1 (0.60) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL28456503 0.70 TP53 (0.33) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL28212336 0.69 TDP1 (0.57) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL3960370 0.69 CHRM1 (0.46) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL8852281 0.68
SCHEMBL4755464 0.67 TDP1 (0.44) CHRM1AKR1A1CHRM3HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9309348-B2 Adhesive composition NIPPON CARBIDE INDUSTRIES CO., INC. (JP) 2016-04-12 US disclosed
EP-2412776-A1 ADHESIVE COMPOSITION Nippon Carbide Industries Co., Inc. (JP) 2012-02-01 EP disclosed
US-20120010341-A1 ADHESIVE COMPOSITION NIPPON CARBIDE INDUSTRIES CO., INC. (JP) 2012-01-12 US disclosed