Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 13/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.47 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | PPARA | Q07869 | 4/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.37 |
| ▸ | PDE1A | P54750 | 1/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754486 | 0.86 | MAPT (0.36) | PPARDFFAR1PPARGPPARAMAPT | |
| SCHEMBL1765914 | 0.82 | PPARD (0.57) | PPARDFFAR1PPARGPPARA | |
| SCHEMBL4754462 | 0.80 | PPARD (0.61) | PPARDFFAR1PPARGPPARA | |
| SCHEMBL1765870 | 0.79 | PPARD (0.49) | PPARDFFAR1PPARGPPARAMAPT | |
| SCHEMBL4754541 | 0.77 | PPARA (0.49) | PPARDPPARGPPARA | |
| SCHEMBL12732403 | 0.75 | PPARD (0.50) | PPARDFFAR1PPARGPPARA | |
| SCHEMBL2464883 | 0.75 | PPARD (0.41) | PPARDFFAR1PPARGPPARA | |
| SCHEMBL12732568 | 0.73 | PPARD (0.45) | PPARDFFAR1PPARGPPARAMAPT | |
| SCHEMBL12732549 | 0.73 | PPARA (0.52) | PPARDPPARGPPARA | |
| SCHEMBL12732398 | 0.73 | MAPT (0.44) | PPARDFFAR1PPARGPPARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008154023-A1 | NOVEL USES OF PPAR DELTA AGONISTS | CERENIS THERAPEUTICS S.A. (FR) | 2008-12-18 | — | — | WO | disclosed |