Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 4/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754485 | 0.86 | PPARD (0.47) | MAPTPPARDPPARGPPARAFFAR1 | |
| SCHEMBL3522998 | 0.76 | PPARD (0.47) | MAPTPPARDPPARGPPARAFFAR1 | |
| SCHEMBL2467699 | 0.76 | PPARD (0.44) | MAPTPPARDPPARGPPARAFFAR1 | |
| SCHEMBL4754541 | 0.75 | PPARA (0.49) | PPARDPPARGPPARA | |
| SCHEMBL1765872 | 0.73 | PPARD (0.41) | MAPTALOX5PPARDPPARGPPARA | |
| SCHEMBL4809536 | 0.71 | PPARD (0.37) | MAPTPPARDPPARGPPARATP53 | |
| SCHEMBL12732398 | 0.71 | MAPT (0.44) | MAPTPPARDPPARGPPARATRPM8 | |
| SCHEMBL12732549 | 0.71 | PPARA (0.52) | PPARDPPARGPPARA | |
| SCHEMBL4754145 | 0.70 | PPARD (0.37) | MAPTPPARDPPARGPPARATRPM8 | |
| SCHEMBL12732403 | 0.70 | PPARD (0.50) | PPARDPPARGPPARAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008154023-A1 | NOVEL USES OF PPAR DELTA AGONISTS | CERENIS THERAPEUTICS S.A. (FR) | 2008-12-18 | — | — | WO | disclosed |