Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITPR3 | Q14573 | 8/20 | 0.90 |
| ▸ | ITPR2 | Q14571 | 4/20 | 0.90 |
| ▸ | ITPR1 | Q14643 | 4/20 | 0.90 |
| ▸ | INPP5A | Q14642 | 3/20 | 0.90 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.89 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.80 |
| ▸ | AKT1 | P31749 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29165997 | 1.00 | ITPR3 (0.90) | ITPR3ITPR2ITPR1INPP5ASMPD1 | |
| SCHEMBL9872231 | 1.00 | ITPR3 (0.90) | ITPR3ITPR2ITPR1INPP5ASMPD1 | |
| SCHEMBL1149378 | 1.00 | ITPR3 (0.90) | ITPR3ITPR2ITPR1INPP5ASMPD1 | |
| SCHEMBL15762968 | 1.00 | ITPR3 (0.90) | ITPR3ITPR2ITPR1INPP5ASMPD1 | |
| SCHEMBL12871334 | 1.00 | ITPR3 (0.90) | ITPR3ITPR2ITPR1INPP5ASMPD1 | |
| SCHEMBL5003539 | 1.00 | ITPR3 (0.90) | ITPR3ITPR2ITPR1INPP5ASMPD1 | |
| SCHEMBL12858863 | 1.00 | ITPR3 (0.90) | ITPR3ITPR2ITPR1INPP5ASMPD1 | |
| SCHEMBL452334 | 1.00 | ITPR3 (0.90) | ITPR3ITPR2ITPR1INPP5ASMPD1 | |
| SCHEMBL113868 | 0.97 | ITPR3 (0.89) | ITPR3ITPR2ITPR1INPP5ASMPD1 | |
| SCHEMBL14396732 | 0.97 | ITPR3 (0.89) | ITPR3ITPR2ITPR1INPP5ASMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0627922-A1 | A PHARMACEUTICAL COMPOSITION WITH IMPROVED BIOAVAILABILITY OF INOSITOL PHOSPHATE | PERSTORP AB (SE) | 1994-12-14 | — | — | EP | claimed |
| WO-2008153906-A1 | HAPTOGLOBIN GENOTYPING FOR PROGNOSIS AND TREATMENT OF CHRONIC VASOSPASM FOLLOWING SUBARACHNOID HEMORRHAGE (SAH) | RAPPAPORT FAMILY INSTITUTE FOR RESEARCH IN THE MEDICAL SCIENCES (IL) | 2008-12-18 | — | — | WO | disclosed |
| EP-0797443-A1 | A PHARMACEUTICAL COMPOSITION WITH IMPROVED BIO-AVAILABILITY OF INOSITOL PHOSPHATE | PERSTORP AB (SE) | 1997-10-01 | — | — | EP | disclosed |
| EP-0730460-A1 | THE USE OF AN ESTER OF INOSITOLTRISPHOSPHATE FOR THE TREATMENT OF INFLAMMATORY CONDITIONS | PERSTORP AB (SE) | 1996-09-11 | — | — | EP | disclosed |
| EP-0724445-A1 | THE USE OF INOSITOLTRISPHOSPHATE FOR THE PREPARING OF MEDICAMENTS | PERSTORP AB (SE) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995019775-A1 | A PHARMACEUTICAL COMPOSITION WITH IMPROVED BIO-AVAILABILITY OF INOSITOL PHOSPHATE | PERSTORP AB (SE) | 1995-07-27 | — | — | WO | disclosed |
| WO-1995014477-A1 | THE USE OF AN ESTER OF INOSITOLTRISPHOSPHATE FOR THE TREATMENT OF INFLAMMATORY CONDITIONS | PERSTORP AB (SE) | 1995-06-01 | — | — | WO | disclosed |
| WO-1995010285-A1 | THE USE OF INOSITOLTRISPHOSPHATE FOR THE PREPARING OF MEDICAMENTS | PERSTORP AB (SE) | 1995-04-20 | — | — | WO | disclosed |
| EP-0536269-A1 | THE USE OF INOSITOLTRISPHOSPHATE FOR THE PREPARING OF MEDICAMENTS | PERSTORP AB (SE) | 1993-04-14 | — | — | EP | disclosed |
| US-5128332-A | Method of treating cardiovascular diseases using inositoltrisphosphate | PERSTORP AB (SE) | 1992-07-07 | — | — | US | disclosed |
| WO-1992000079-A1 | THE USE OF INOSITOLTRISPHOSPHATE FOR THE PREPARING OF MEDICAMENTS | PERSTORP AB (SE) | 1992-01-09 | — | — | WO | disclosed |