Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 19/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.66 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.66 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754571 | 1.00 | OPRM1 (0.66) | OPRM1KCNH2OPRD1OPRK1 | |
| SCHEMBL4697675 | 0.92 | OPRM1 (0.75) | OPRM1KCNH2OPRD1OPRK1 | |
| SCHEMBL4697672 | 0.92 | OPRM1 (0.75) | OPRM1KCNH2OPRD1OPRK1 | |
| SCHEMBL4702514 | 0.86 | OPRM1 (0.84) | OPRM1KCNH2OPRD1OPRK1 | |
| SCHEMBL4754570 | 0.83 | OPRM1 (0.58) | OPRM1KCNH2OPRD1OPRK1 | |
| SCHEMBL5486421 | 0.80 | KCNH2 (0.74) | OPRM1KCNH2OPRD1OPRK1 | |
| SCHEMBL5486420 | 0.80 | KCNH2 (0.74) | OPRM1KCNH2OPRD1OPRK1 | |
| SCHEMBL5851486 | 0.80 | OPRM1 (0.71) | OPRM1KCNH2OPRD1OPRK1 | |
| SCHEMBL4697594 | 0.80 | OPRM1 (1.00) | OPRM1KCNH2OPRD1OPRK1 | |
| SCHEMBL4698408 | 0.80 | OPRM1 (0.74) | OPRM1KCNH2OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1440059-B1 | 3-AZABICYCLO(3.1.0)HEXANE DERIVATIVES AS OPIOID RECEPTOR ANTAGONISTS | PFIZER PROD INC (US) | 2008-04-16 | — | — | EP | disclosed |