Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15730110 | 0.81 | LMNA (0.35) | LMNAGAADPP4DPP8DPP7 | |
| SCHEMBL15730230 | 0.73 | CYP1A2 (0.35) | LMNAGAATSHRNPSR1POLB | |
| SCHEMBL19229475 | 0.73 | GAA (0.35) | GAAADRA1APDE10A | |
| SCHEMBL18328205 | 0.73 | CYP1A2 (0.41) | LMNAGAATSHRNPSR1TDP1 | |
| SCHEMBL15730331 | 0.73 | LMNA (0.51) | LMNAGAATSHRNPSR1POLB | |
| SCHEMBL14401055 | 0.73 | LMNA (0.55) | LMNAGAATSHRNPSR1TDP1 | |
| SCHEMBL15730354 | 0.72 | LMNA (0.35) | LMNAGAADPP4DPP8DPP7 | |
| SCHEMBL15730380 | 0.72 | TSHR (0.40) | LMNAGAADPP4DPP8DPP7 | |
| SCHEMBL18328249 | 0.71 | LMNA (0.56) | LMNAGAATSHRNPSR1TDP1 | |
| SCHEMBL15730538 | 0.71 | LMNA (0.56) | LMNAGAATSHRNPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008148832-A1 | COMPOUNDS WHICH POTENTIATE AMPA RECEPTOR AND USES THEROF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2008-12-11 | — | — | WO | disclosed |