Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7236597 | 0.90 | ALDH1A1 (0.51) | FUCA1ALDH1A1SLC18A3ACHEGBA1 | |
| SCHEMBL15140479 | 0.85 | FUCA1 (0.57) | FUCA1ALDH1A1SLC18A3ACHEGBA1 | |
| SCHEMBL15140481 | 0.85 | FUCA1 (0.57) | FUCA1ALDH1A1SLC18A3ACHEGBA1 | |
| SCHEMBL15140480 | 0.85 | FUCA1 (0.57) | FUCA1ALDH1A1SLC18A3ACHEGBA1 | |
| SCHEMBL458459 | 0.84 | GBA1 (0.66) | FUCA1ALDH1A1SLC18A3ACHEGBA1 | |
| SCHEMBL505547 | 0.84 | GBA1 (0.66) | FUCA1ALDH1A1SLC18A3ACHEGBA1 | |
| SCHEMBL1315584 | 0.84 | GBA1 (0.66) | FUCA1ALDH1A1SLC18A3ACHEGBA1 | |
| SCHEMBL1315585 | 0.84 | GBA1 (0.66) | FUCA1ALDH1A1SLC18A3ACHEGBA1 | |
| SCHEMBL5999883 | 0.84 | FUCA1 (0.58) | FUCA1ALDH1A1SLC18A3ACHEGBA1 | |
| SCHEMBL5999878 | 0.84 | FUCA1 (0.58) | FUCA1ALDH1A1SLC18A3ACHEGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156832-A2 | RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |