Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 19/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4789483 | 0.97 | AURKA (0.55) | AURKA | |
| SCHEMBL4790505 | 0.90 | AURKA (0.54) | AURKA | |
| SCHEMBL212793 | 0.89 | AURKA (0.59) | AURKAKDRAURKB | |
| SCHEMBL4756460 | 0.88 | AURKA (0.43) | AURKAKDRAURKB | |
| SCHEMBL208400 | 0.88 | AURKA (0.60) | AURKA | |
| SCHEMBL4757483 | 0.87 | AURKA (0.59) | AURKA | |
| SCHEMBL209796 | 0.87 | AURKA (0.44) | AURKAKDRAURKB | |
| SCHEMBL208920 | 0.86 | AURKA (0.74) | AURKA | |
| SCHEMBL4756080 | 0.86 | AURKA (0.61) | AURKAAURKB | |
| SCHEMBL209623 | 0.86 | AURKA (0.45) | AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001021-A1 | IMIDAZOPYRIDINE DERIVATIVES USEFUL AS ENZYME INHIBITORS FOR THE TREATMENT OF CELL PROLIFERATIVE AND AUTOIMMUNE DISEASES | CHROMA THERAPEUTICS LTD. (GB) | 2008-12-31 | — | — | WO | disclosed |