Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 20/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.54 |
| ▸ | FLT3 | P36888 | 1/20 | 0.54 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | AURKC | Q9UQB9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL208679 | 0.89 | AURKA (0.77) | AURKAKCNH2FLT3 | |
| SCHEMBL13985590 | 0.87 | AURKA (0.76) | AURKAKCNH2FLT3AURKBAURKC | |
| SCHEMBL4754664 | 0.86 | AURKA (0.56) | AURKAAURKB | |
| SCHEMBL209623 | 0.86 | AURKA (0.45) | AURKA | |
| SCHEMBL13985734 | 0.86 | AURKA (0.77) | AURKAKCNH2FLT3AURKBAURKC | |
| SCHEMBL208400 | 0.84 | AURKA (0.60) | AURKA | |
| SCHEMBL209196 | 0.84 | AURKA (0.78) | AURKAKCNH2FLT3AURKBAURKC | |
| SCHEMBL209542 | 0.84 | AURKA (0.76) | AURKAKCNH2FLT3 | |
| SCHEMBL13985737 | 0.84 | AURKA (0.55) | AURKAKCNH2FLT3AURKBAURKC | |
| SCHEMBL4757466 | 0.84 | AURKA (0.64) | AURKAKCNH2FLT3AURKBAURKC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001021-A1 | IMIDAZOPYRIDINE DERIVATIVES USEFUL AS ENZYME INHIBITORS FOR THE TREATMENT OF CELL PROLIFERATIVE AND AUTOIMMUNE DISEASES | CHROMA THERAPEUTICS LTD. (GB) | 2008-12-31 | — | — | WO | disclosed |