Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.36 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4669576 | 1.00 | MEN1 (0.43) | MEN1KMT2AHDAC4MEF2DCYP1A2 | |
| SCHEMBL4015839 | 0.90 | MEN1 (0.44) | MEN1KMT2AHDAC4MEF2DMMP1 | |
| SCHEMBL4015068 | 0.90 | MEN1 (0.44) | MEN1KMT2AHDAC4MEF2DCYP1A2 | |
| SCHEMBL4016848 | 0.90 | MEN1 (0.44) | MEN1KMT2AHDAC4MEF2DCYP1A2 | |
| SCHEMBL4019849 | 0.90 | MEN1 (0.44) | MEN1KMT2AHDAC4MEF2DCYP1A2 | |
| SCHEMBL4017825 | 0.87 | MMP1 (0.50) | MEN1KMT2AHDAC4MEF2DMMP1 | |
| SCHEMBL4017819 | 0.87 | MEN1 (0.47) | MEN1KMT2AHDAC4MMP1POLB | |
| SCHEMBL4669526 | 0.86 | APP (0.42) | MEN1KMT2AHDAC4MEF2DMMP1 | |
| SCHEMBL4014345 | 0.86 | MMP1 (0.48) | MEN1KMT2AMMP1MMP2MMP9 | |
| SCHEMBL4017820 | 0.86 | MAPT (0.50) | MEN1KMT2ACYP1A2CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008152097-A1 | CINNAMIC ACID DERIVATIVES AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-12-18 | — | — | WO | claimed |
| WO-2008152097-A1 | CINNAMIC ACID DERIVATIVES AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-12-18 | — | — | WO | disclosed |