Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.34 |
| ▸ | MEF2D | Q14814 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4669474 | 1.00 | MEN1 (0.42) | MEN1KMT2AHDAC1L3MBTL1CYP2C19 | |
| SCHEMBL4669255 | 0.90 | MEN1 (0.41) | MEN1KMT2AHDAC1L3MBTL1CYP2C19 | |
| SCHEMBL4754383 | 0.90 | MEN1 (0.41) | MEN1KMT2AHDAC1L3MBTL1CYP2C19 | |
| SCHEMBL4668517 | 0.89 | MEN1 (0.43) | MEN1KMT2AHDAC1L3MBTL1CYP2C19 | |
| SCHEMBL4755393 | 0.89 | MEN1 (0.43) | MEN1KMT2AHDAC1L3MBTL1CYP2C19 | |
| SCHEMBL13982589 | 0.88 | MEN1 (0.43) | MEN1KMT2AHDAC1CYP2C19CYP1A2 | |
| SCHEMBL4787699 | 0.86 | MEN1 (0.43) | MEN1KMT2AHDAC1L3MBTL1CYP2C19 | |
| SCHEMBL4787706 | 0.86 | MEN1 (0.43) | MEN1KMT2AHDAC1L3MBTL1CYP2C19 | |
| SCHEMBL4787691 | 0.86 | MEN1 (0.43) | MEN1KMT2AHDAC1L3MBTL1CYP2C19 | |
| SCHEMBL4017825 | 0.86 | MMP1 (0.50) | MEN1KMT2AL3MBTL1POLBMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008152097-A1 | CINNAMIC ACID DERIVATIVES AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-12-18 | — | — | WO | claimed |
| WO-2008152097-A1 | CINNAMIC ACID DERIVATIVES AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-12-18 | — | — | WO | disclosed |