Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754838 | 0.82 | POLB (0.51) | MAPK1KMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL20427862 | 0.81 | PDE4D (0.50) | PDE4DMAPK1PDE4BHPGDSMN1; SMN2 | |
| SCHEMBL22979354 | 0.80 | PDE4D (0.55) | PDE4DMAPK1PDE4BHPGDSMN1; SMN2 | |
| SCHEMBL18782037 | 0.77 | PDE4D (0.54) | PDE4DMAPK1PDE4BHPGDSMN1; SMN2 | |
| SCHEMBL20551488 | 0.77 | MAPK1 (0.43) | PDE4DMAPK1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL14440775 | 0.76 | PDE4D (0.51) | PDE4DMAPK1PDE4BHPGDSMN1; SMN2 | |
| SCHEMBL8784515 | 0.75 | PDE4D (0.56) | PDE4DMAPK1PDE4BHPGDSMN1; SMN2 | |
| SCHEMBL18764828 | 0.75 | PDE4D (0.50) | PDE4DMAPK1PDE4BHPGDSMN1; SMN2 | |
| SCHEMBL18740310 | 0.73 | MAPK1 (0.54) | PDE4DMAPK1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL18764922 | 0.72 | PDE4D (0.42) | PDE4DMAPK1PDE4BHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157273-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |