Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 2/20 | 0.34 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754855 | 0.82 | PDE4D (0.48) | MEN1KMT2AGAAALDH1A1LMNA | |
| SCHEMBL20378348 | 0.80 | POLB (0.57) | POLBMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL19119188 | 0.80 | POLB (0.57) | POLBMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL28015987 | 0.77 | POLB (0.54) | POLBMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL8306766 | 0.75 | POLB (0.60) | POLBMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL354838 | 0.73 | POLB (0.50) | POLBMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL353583 | 0.72 | POLB (0.49) | POLBMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL20551504 | 0.71 | GABRP (0.33) | GAAMAPK1 | |
| SCHEMBL20378245 | 0.70 | POLB (0.54) | POLBMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL1335845 | 0.69 | KDM4E (0.60) | POLBMEN1KMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157273-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |