Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A7 | Q99884 | 18/20 | 0.63 |
| ▸ | SMO | Q99835 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754888 | 1.00 | SLC6A7 (0.63) | SLC6A7SMOALDH1A1TSHRNAMPT | |
| SCHEMBL3575473 | 0.89 | SLC6A7 (0.60) | SLC6A7SMOALDH1A1TSHR | |
| SCHEMBL3575476 | 0.89 | SLC6A7 (0.60) | SLC6A7SMOALDH1A1TSHR | |
| SCHEMBL3585161 | 0.87 | SLC6A7 (0.60) | SLC6A7SMOALDH1A1TSHR | |
| SCHEMBL3585156 | 0.87 | SLC6A7 (0.60) | SLC6A7SMOALDH1A1TSHR | |
| SCHEMBL3579344 | 0.86 | SLC6A7 (0.74) | SLC6A7SMOALDH1A1TSHR | |
| SCHEMBL3579341 | 0.86 | SLC6A7 (0.74) | SLC6A7SMOALDH1A1TSHR | |
| SCHEMBL3580071 | 0.86 | SLC6A7 (0.74) | SLC6A7SMOALDH1A1TSHR | |
| SCHEMBL3585370 | 0.84 | SLC6A7 (0.63) | SLC6A7SMOALDH1A1TSHRNAMPT | |
| SCHEMBL3585367 | 0.84 | SLC6A7 (0.63) | SLC6A7SMOALDH1A1TSHRNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893212-A2 | MULTICYCLIC COMPOUNDS AND METHODS OF THEIR USE | Lexicon Pharmaceuticals, Inc. (US) | 2008-03-05 | — | — | EP | claimed |
| WO-2006124748-A2 | MULTICYCLIC COMPOUNDS AND METHODS OF THEIR USE | LEXICON GENETICS INCORPORATED (US) | 2006-11-23 | — | — | WO | claimed |