SCHEMBL4755

SCHEMBL4755

CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)O)C(C)O

nearest known ligand 0.73

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 17/20 0.72
CCKBR P32239 1/20 0.71
GCGR P47871 5/20 0.70
GIPR P48546 1/20 0.70
NR3C1 P04150 2/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23721788 1.00 GLP1R (0.72) GLP1RCCKBRGCGRGIPRNR3C1
Zinc Ion SCHEMBL3043764 1.00 GLP1R (0.72) GLP1RCCKBRGCGRGIPRNR3C1
Hydrochloric Acid SCHEMBL20883 1.00 GLP1R (0.72) GLP1RCCKBRGCGRGIPRNR3C1
Glycine SCHEMBL9450801 1.00 GLP1R (0.72) GLP1RCCKBRGCGRGIPRNR3C1
SCHEMBL6432383 1.00 GLP1R (0.72) GLP1RCCKBRGCGRGIPRNR3C1
SCHEMBL30721605 1.00 GLP1R (0.73) GLP1RCCKBRGCGRGIPRNR3C1
Acetic Acid SCHEMBL4351476 0.99 GLP1R (0.71) GLP1RCCKBRGCGRGIPRNR3C1
Hydrochloric Acid SCHEMBL4743028 0.99 GLP1R (0.71) GLP1RCCKBRGCGRGIPRNR3C1
Hydrochloric Acid SCHEMBL4743032 0.99 GLP1R (0.71) GLP1RCCKBRGCGRGIPRNR3C1
SCHEMBL20945961 0.98 GLP1R (0.71) GLP1RCCKBRGCGRGIPRNR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 120121 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144877-A1 HIGH CAPACITY DIKETOPIPERAZINE MICROPARTICLES AND METHODS MANNKIND CORPORATION (US) 2026-05-28 US claimed
EP-3594323-B1 METHODS AND COMPOSITIONS FOR GENERATING PANCREATIC PROGENITORS AND FUNCTIONAL BETA CELLS FROM HPSCS UNIV HEALTH NETWORK (CA) 2026-05-27 EP claimed
EP-4748438-A2 ENTERICALLY DELIVERED BITTER OLIGOPEPTIDES FOR THE TREATMENT FOR TYPE 2 DIABETES Cedars-Sinai Medical Center (US) 2026-05-27 EP claimed
CN-122081170-A Two strains of intestinal bacteria with blood sugar reducing function for transplanting healthy donor bifidobacterium bifidum WD001 and bifidobacterium animalis subspecies lactis WD002 and application thereof 2026-05-26 CN claimed
CN-122075410-A Dry powder composition for intranasal delivery 2026-05-26 CN claimed
CN-116850183-B Methods and pharmaceutical compositions for treating myopia GRAND PHARMA (CHINA) Co.,Ltd. (CN) 2026-05-26 CN claimed
US-12635940-B2 Closed-loop drug infusion system with synergic control UNIVERSIDAD POLITÉCNICA DE MADRID FUNDACION PARA LA INVESTIGACIÓN E INNOVACIÓN BIOMÉDICA (ES) 2026-05-26 US claimed
US-12637662-B2 Cells, islets, and organoids that evade immune detection and autoimmunity, methods of production and use thereof SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2026-05-26 US claimed
CN-114974464-B Method and apparatus for predicting antagonists, medium and device LANZHOU UNIVERSITY (CN) 2026-05-26 CN claimed
CN-116698563-B Method for detecting polypeptide by capillary gel electrophoresis ZHEJIANG UNIVERSITY (CN) 2026-05-26 CN claimed
WO-1980000791-A1 B-GLUCURONIDASE ACTIVITY AND/OR PH-DEPENDENT PHARMACEUTICALS AND THEIR METHODS OF PRODUCTION AND USE FOR SELECTIVE TREATMENT OF DISEASES SCHWIMMER A (US) 1980-05-01 WO claimed
EP-0009147-A2 A method for enzyme immunoassay of pancreatic glucagon and a peptide-enzyme conjugate usable for the method Takeda Chemical Industries, Ltd. (JP) 1980-04-02 EP claimed
US-4179337-A POLYALKYLENE GLYCOL LINKED TO POLYPEPTIDE THROUGH COUPLER RESEARCH CORPORATION TECHNOLOGIES, INC., A NOT-FOR-PROFIT, NON-STOCK CORP. OF DE 1979-12-18 US claimed
US-4159979-A P-METHYLBENZYLSULFONYL GROUP FOR AMINO GROUPS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1979-07-03 US claimed
EP-0001295-A2 Somatostatin-like cyclopeptides, a process for their preparation, pharmaceutical compositions containing them, and their therapeutical application CIBA-GEIGY AG (CH) 1979-04-04 EP claimed
US-4129560-A BY ION EXCHANGER CHROMATOGRAPHY HOECHST AKTIENGESELLSCHAFT (DE) 1978-12-12 US claimed
US-4118495-A Method of treating hyperglucagonemia with 1,3-dioxo-1H-benz[de]-isoquinoline-2(3H)-acetic acid AYERST, MCKENNA & HARRISON LIMITED (CA) 1978-10-03 US claimed
US-4105606-A ADHESIVE FOR THE MANUFACTURE OF PLYWOOD, PARTICLE BOARDS, FIBER BOARDS AND SIMILAR PRODUCTS KESKUSLABORATORIO-CENTRALLABORATORIUM AB (FI) 1978-08-08 US claimed
US-4033941-A ALKALINE GEL FILTRATION ELI LILLY AND COMPANY (US) 1977-07-05 US claimed
US-4000259-A DIABETES AMERICAN HOME PRODUCTS CORPORATION (US) 1976-12-28 US claimed