Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5515355 | 0.93 | REN (0.64) | REN | |
| SCHEMBL968278 | 0.88 | REN (0.68) | RENCYP3A4 | |
| SCHEMBL968276 | 0.88 | REN (0.68) | RENCYP3A4 | |
| SCHEMBL4789098 | 0.88 | REN (0.69) | RENCYP3A4 | |
| SCHEMBL27758544 | 0.88 | REN (0.69) | RENCYP3A4 | |
| SCHEMBL5515427 | 0.88 | REN (0.65) | REN | |
| SCHEMBL2997291 | 0.81 | REN (0.81) | REN | |
| SCHEMBL2997292 | 0.81 | REN (0.81) | REN | |
| SCHEMBL2995552 | 0.81 | REN (0.81) | REN | |
| SCHEMBL2989415 | 0.81 | REN (0.81) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156832-A2 | RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |