Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.46 |
| ▸ | PPARD | Q03181 | 5/20 | 0.46 |
| ▸ | PPARA | Q07869 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.31 |
| ▸ | PDE11A | Q9HCR9 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12732399 | 0.88 | PPARG (0.49) | PPARGPPARDPPARAMAPTGAA | |
| SCHEMBL20815372 | 0.86 | PPARD (0.47) | PPARGPPARDPPARAMAPTNPC1 | |
| SCHEMBL4755260 | 0.85 | PPARG (0.49) | PPARGPPARDPPARAMAPTSMN1; SMN2 | |
| SCHEMBL2463427 | 0.84 | PPARG (0.46) | PPARGPPARDPPARAMAPTGAA | |
| SCHEMBL24658330 | 0.84 | PPARG (0.48) | PPARGPPARDPPARAMAPTGAA | |
| SCHEMBL4755223 | 0.84 | PPARA (0.53) | PPARGPPARDPPARAMAPTNPC1 | |
| SCHEMBL2460899 | 0.84 | PPARD (0.59) | PPARGPPARDPPARAMAPTKDM4E | |
| SCHEMBL30003514 | 0.84 | PPARG (0.48) | PPARGPPARDPPARAMAPTGAA | |
| SCHEMBL2491414 | 0.84 | PPARG (0.45) | PPARGPPARDPPARAMAPTGAA | |
| SCHEMBL1765866 | 0.83 | PPARA (0.45) | PPARGPPARDPPARAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008154023-A1 | NOVEL USES OF PPAR DELTA AGONISTS | CERENIS THERAPEUTICS S.A. (FR) | 2008-12-18 | — | — | WO | disclosed |