Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 15/20 | 0.69 |
| ▸ | PDE4B | Q07343 | 15/20 | 0.53 |
| ▸ | PDE4A | P27815 | 13/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 12/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4032324 | 1.00 | PDE4D (0.69) | PDE4DPDE4BPDE4APDE4CMEN1 | |
| SCHEMBL14457761 | 0.91 | PDE4D (0.57) | PDE4DPDE4BPDE4APDE4CMEN1 | |
| SCHEMBL4033314 | 0.89 | PDE4D (0.59) | PDE4DPDE4BPDE4APDE4CPDE11A | |
| SCHEMBL4026556 | 0.86 | PDE4D (0.73) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL14364604 | 0.85 | PDE4D (0.49) | PDE4DPDE4BPDE4APDE4CMEN1 | |
| SCHEMBL5017953 | 0.84 | PDE4D (0.73) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL5017912 | 0.84 | PDE4B (0.71) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL5018033 | 0.84 | PDE4D (0.70) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL4030622 | 0.84 | PDE4D (0.80) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL6526531 | 0.84 | PDE4D (0.55) | PDE4DPDE4BPDE4APDE4CSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008005955-A9 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS | FOREST LAB HOLDINGS LTD | 2008-04-03 | — | — | WO | disclosed |
| WO-2008005955-A2 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2008-01-10 | — | — | WO | disclosed |