Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.39 |
| ▸ | CTSC | P53634 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755477 | 1.00 | HSD11B1 (0.39) | HSD11B1CTSCMAPTKDM4ELMNA | |
| SCHEMBL4755475 | 1.00 | HSD11B1 (0.39) | HSD11B1CTSCMAPTKDM4ELMNA | |
| SCHEMBL4755521 | 0.74 | USP2 (0.42) | HSD11B1LMNAGBA1LTB4RLTB4R2 | |
| SCHEMBL5445647 | 0.74 | USP2 (0.42) | HSD11B1LMNAGBA1LTB4RLTB4R2 | |
| SCHEMBL4755518 | 0.74 | USP2 (0.42) | HSD11B1LMNAGBA1LTB4RLTB4R2 | |
| SCHEMBL4755526 | 0.74 | USP2 (0.42) | HSD11B1LMNAGBA1LTB4RLTB4R2 | |
| SCHEMBL4754114 | 0.74 | HSD11B1 (0.40) | HSD11B1MAPTHTT | |
| SCHEMBL4756989 | 0.72 | POLB (0.33) | CTSCMAPTKDM4EMEN1KMT2A | |
| SCHEMBL4756985 | 0.72 | POLB (0.33) | CTSCMAPTKDM4EMEN1KMT2A | |
| SCHEMBL4756195 | 0.71 | HSD11B1 (0.38) | HSD11B1MAPTAKR1B1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008155619-A2 | PREPARATION OF OPTICALLY-ACTIVE CYCLIC AMINO ACIDS | PFIZER INC. (US) | 2008-12-24 | — | — | WO | claimed |
| WO-2008155619-A2 | PREPARATION OF OPTICALLY-ACTIVE CYCLIC AMINO ACIDS | PFIZER INC. (US) | 2008-12-24 | — | — | WO | disclosed |