Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755416 | 0.98 | BRD9 (0.35) | FFAR1HTR1AHTR1DHTR1BCNR2 | |
| SCHEMBL13983542 | 0.95 | JAK2 (0.31) | JAK2JAK3NTRK1 | |
| SCHEMBL13983521 | 0.89 | SLC9A3 (0.34) | FFAR1HTR1AHTR1DHTR1BBRD9 | |
| SCHEMBL4753628 | 0.87 | FFAR1 (0.34) | FFAR1 | |
| SCHEMBL13983564 | 0.86 | FFAR1 (0.38) | FFAR1HTR1AHTR1DHTR1BBRD9 | |
| SCHEMBL4755591 | 0.85 | BRD9 (0.33) | FFAR1BRD9 | |
| SCHEMBL13983525 | 0.84 | FFAR1 (0.36) | FFAR1BRD9FFAR4JAK2JAK3 | |
| SCHEMBL13983559 | 0.84 | FFAR1 (0.34) | FFAR1HTR1AHTR1DHTR1BCNR2 | |
| SCHEMBL13983099 | 0.82 | TRPV1 (0.37) | FFAR1CNR2BRD9FFAR4JAK2 | |
| SCHEMBL4756392 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008151927-A2 | 6-N-SUBSTITUTED BENZ IMIDAZOLE DERIVATIVES AS ACID PUMP ANTAGONISTS | NYCOMED GMBH (DE) | 2008-12-18 | — | — | WO | disclosed |
| WO-2008151927-A2 | 6-N-SUBSTITUTED BENZ IMIDAZOLE DERIVATIVES AS ACID PUMP ANTAGONISTS | NYCOMED GMBH (DE) | 2008-12-18 | — | — | WO | disclosed |