SCHEMBL4755591

SCHEMBL4755591

Cc1nc2c(OC3CCOc4cc(F)cc(F)c43)cc(N3CCCCC3=O)cc2n1C

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
BRD9 Q9H8M2 1/20 0.33
FFAR1 O14842 1/20 0.32
PIK3CA P42336 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4753628 0.98 FFAR1 (0.34) FFAR1
SCHEMBL4756392 0.94
SCHEMBL13983525 0.90 FFAR1 (0.36) BRD9FFAR1
SCHEMBL13983564 0.87 FFAR1 (0.38) BRD9FFAR1
SCHEMBL4755416 0.87 BRD9 (0.35) BRD9FFAR1
SCHEMBL4755502 0.85 FFAR1 (0.34) BRD9FFAR1
SCHEMBL13983522 0.84 FFAR1 (0.32) FFAR1PIK3CA
SCHEMBL13983544 0.84 FFAR1 (0.33) FFAR1
SCHEMBL13983280 0.82 BRD9 (0.33) BRD9PIK3CA
SCHEMBL13983562 0.82 FFAR1 (0.34) FFAR1PIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008151927-A2 6-N-SUBSTITUTED BENZ IMIDAZOLE DERIVATIVES AS ACID PUMP ANTAGONISTS NYCOMED GMBH (DE) 2008-12-18 WO disclosed
WO-2008151927-A2 6-N-SUBSTITUTED BENZ IMIDAZOLE DERIVATIVES AS ACID PUMP ANTAGONISTS NYCOMED GMBH (DE) 2008-12-18 WO disclosed