Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4413889 | 0.84 | KDM4E (0.56) | KDM4EMEN1KMT2AKCNA5ALOX15 | |
| SCHEMBL4404341 | 0.83 | KDM4E (0.50) | KDM4EMEN1KMT2AKCNA5ALOX15 | |
| SCHEMBL4413514 | 0.83 | KDM4E (0.50) | KDM4EMEN1KMT2AKCNA5ALOX15 | |
| SCHEMBL14293672 | 0.81 | KDM4E (0.52) | KDM4EMEN1KMT2AKCNA5ALOX15 | |
| SCHEMBL4409089 | 0.80 | CHRM2 (0.57) | KDM4EMEN1KMT2AALOX15TDP1 | |
| SCHEMBL4414847 | 0.77 | KDM4E (0.42) | KDM4EMEN1KMT2AKCNA5ALOX15 | |
| SCHEMBL13900437 | 0.77 | NPSR1 (0.56) | KDM4EMEN1KMT2AALOX15TDP1 | |
| SCHEMBL4404505 | 0.77 | CHRM2 (0.53) | KDM4EMEN1KMT2AALOX15TDP1 | |
| SCHEMBL4515742 | 0.76 | CHRM2 (0.55) | KDM4EMEN1KMT2AALOX15TDP1 | |
| SCHEMBL825189 | 0.75 | SMN1; SMN2 (0.68) | KDM4EMEN1KMT2AALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021788-A2 | POLYAMINE COMPOUNDS | TAIGEN BIOTECHNOLOGY CO., LTD. (CN) | 2008-02-21 | — | — | WO | disclosed |