Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755724 | 1.00 | SMN1; SMN2 (0.39) | SMN1; SMN2TSHR | |
| SCHEMBL4756545 | 0.88 | SMN1; SMN2 (0.35) | SMN1; SMN2TSHR | |
| SCHEMBL4756550 | 0.88 | SMN1; SMN2 (0.35) | SMN1; SMN2TSHR | |
| SCHEMBL4753772 | 0.87 | SMN1; SMN2 (0.38) | SMN1; SMN2TSHR | |
| SCHEMBL4753774 | 0.87 | SMN1; SMN2 (0.38) | SMN1; SMN2TSHR | |
| SCHEMBL4755587 | 0.81 | TSHR (0.41) | SMN1; SMN2TSHR | |
| SCHEMBL4755585 | 0.81 | TSHR (0.41) | SMN1; SMN2TSHR | |
| SCHEMBL4753664 | 0.79 | SMN1; SMN2 (0.39) | SMN1; SMN2TSHR | |
| SCHEMBL4753663 | 0.79 | SMN1; SMN2 (0.39) | SMN1; SMN2TSHR | |
| SCHEMBL4753739 | 0.67 | ESR1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |