Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753772 | 1.00 | SMN1; SMN2 (0.38) | SMN1; SMN2TSHRPI4KBPOLBHTT | |
| SCHEMBL4755728 | 0.87 | SMN1; SMN2 (0.39) | SMN1; SMN2TSHR | |
| SCHEMBL4755724 | 0.87 | SMN1; SMN2 (0.39) | SMN1; SMN2TSHR | |
| SCHEMBL4756550 | 0.83 | SMN1; SMN2 (0.35) | SMN1; SMN2TSHR | |
| SCHEMBL4756545 | 0.83 | SMN1; SMN2 (0.35) | SMN1; SMN2TSHR | |
| SCHEMBL4753739 | 0.80 | ESR1 (0.32) | POLBESR1PTGDR2 | |
| SCHEMBL4753740 | 0.80 | ESR1 (0.32) | POLBESR1PTGDR2 | |
| SCHEMBL4755633 | 0.73 | NPSR1 (0.38) | PI4KBPOLBPTGDR2KMT2A | |
| SCHEMBL4755628 | 0.73 | NPSR1 (0.38) | PI4KBPOLBPTGDR2KMT2A | |
| SCHEMBL4755587 | 0.73 | TSHR (0.41) | SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |