Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | EP300 | Q09472 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL588080 | 1.00 | TSHR (0.52) | TSHRTHRBEP300FAAHTRPV1 | |
| SCHEMBL588205 | 1.00 | TSHR (0.52) | TSHRTHRBEP300FAAHTRPV1 | |
| SCHEMBL3181791 | 1.00 | TSHR (0.52) | TSHRTHRBEP300FAAHTRPV1 | |
| SCHEMBL548489 | 1.00 | TSHR (0.52) | TSHRTHRBEP300FAAHTRPV1 | |
| SCHEMBL4756812 | 1.00 | TSHR (0.52) | TSHRTHRBEP300FAAHTRPV1 | |
| SCHEMBL413361 | 1.00 | — | — | |
| SCHEMBL4755732 | 1.00 | TSHR (0.52) | TSHRTHRBEP300FAAHTRPV1 | |
| SCHEMBL4756755 | 1.00 | TSHR (0.52) | TSHRTHRBEP300FAAHTRPV1 | |
| SCHEMBL337456 | 1.00 | TSHR (0.52) | TSHRTHRBEP300FAAHTRPV1 | |
| SCHEMBL167574 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008110612-A2 | NOVEL COMPOUNDS AND LUBRICATING COMPOSITIONS COMPRISING THE SAME | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2008-09-18 | — | — | WO | disclosed |
| EP-0869185-B9 | Production of optically active sphingoid compound | SUMITOMO CHEMICAL CO (JP) | 2004-08-11 | — | — | EP | disclosed |
| EP-0869185-B1 | Production of optically active sphingoid compound | SUMITOMO CHEMICAL CO (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6184008-B1 | USING AN ESTERASE TO TO SELECTIVELY HYDROLYZE AN ENANTIOMER OF AN ESTER OF DEFINED STRUCTURE TO PRODUCE THE ALCOHOL; COSMETICS; MEDICINAL TREATMENTS FOR SKIN AND HAIR; CHEMICAL INTERMEDIATES | SUMITOMO CHEMICAL COMPANY LTD. (JP) | 2001-02-06 | — | — | US | disclosed |
| EP-0869185-A2 | Production of optically active sphingoid compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-10-07 | — | — | EP | disclosed |