Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 7/20 | 0.50 |
| ▸ | KLK5 | Q9Y337 | 6/20 | 0.50 |
| ▸ | TACR1 | P25103 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CPB1 | P15086 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1928743 | 0.93 | KMT2A (0.51) | KLK7KLK5TACR1KMT2AL3MBTL1 | |
| SCHEMBL8280167 | 0.93 | KMT2A (0.51) | KLK7KLK5TACR1KMT2AL3MBTL1 | |
| SCHEMBL14583914 | 0.93 | KMT2A (0.51) | KLK7KLK5TACR1KMT2AL3MBTL1 | |
| SCHEMBL4380010 | 0.93 | KMT2A (0.51) | KLK7KLK5TACR1KMT2AL3MBTL1 | |
| SCHEMBL5435734 | 0.93 | KMT2A (0.54) | KLK7KLK5KMT2AL3MBTL1KDM1A | |
| SCHEMBL5645993 | 0.93 | KMT2A (0.54) | KLK7KLK5KMT2AL3MBTL1KDM1A | |
| SCHEMBL12734545 | 0.93 | KMT2A (0.54) | KLK7KLK5KMT2AL3MBTL1KDM1A | |
| SCHEMBL26926885 | 0.90 | KLK7 (0.48) | KLK7KLK5TACR1KMT2AL3MBTL1 | |
| SCHEMBL31470310 | 0.90 | KMT2A (0.52) | KLK7KLK5TACR1KMT2AL3MBTL1 | |
| SCHEMBL3247211 | 0.84 | KMT2A (0.46) | KLK7KLK5KMT2AL3MBTL1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007754-A1 | 2, 4-DIAMINOPYRIMIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF CANCER | Boehringer Ingelheim International GmbH (DE) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007115999-A1 | 2, 4-DIAMINOPYRIMIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF CANCER | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-10-18 | — | — | WO | disclosed |