Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KLK7 | P49862 | 5/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 4/20 | 0.48 |
| ▸ | MERTK | Q12866 | 9/20 | 0.48 |
| ▸ | AXL | P30530 | 6/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.48 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12734545 | 1.00 | KMT2A (0.54) | KMT2AL3MBTL1KLK7KLK5MERTK | |
| SCHEMBL5435734 | 1.00 | KMT2A (0.54) | KMT2AL3MBTL1KLK7KLK5MERTK | |
| SCHEMBL4380010 | 0.98 | KMT2A (0.51) | KMT2AL3MBTL1KLK7KLK5MERTK | |
| SCHEMBL14583914 | 0.98 | KMT2A (0.51) | KMT2AL3MBTL1KLK7KLK5MERTK | |
| SCHEMBL8280167 | 0.98 | KMT2A (0.51) | KMT2AL3MBTL1KLK7KLK5MERTK | |
| SCHEMBL1928743 | 0.98 | KMT2A (0.51) | KMT2AL3MBTL1KLK7KLK5MERTK | |
| SCHEMBL4755871 | 0.93 | KLK7 (0.50) | KMT2AL3MBTL1KLK7KLK5KDM1A | |
| SCHEMBL24437025 | 0.88 | AXL (0.43) | KMT2AL3MBTL1KLK7KLK5MERTK | |
| SCHEMBL30861499 | 0.88 | CACNA1B (0.48) | KMT2AL3MBTL1KLK7KLK5MERTK | |
| SCHEMBL31470310 | 0.87 | KMT2A (0.52) | KMT2AL3MBTL1KLK7KLK5KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312214-B2 | 1, 1-disubstituted cycloalkyl derivatives as factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-12-25 | — | — | US | disclosed |