Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | KDM6A | O15550 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | COMT | P21964 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7554482 | 0.85 | MMP1 (0.40) | MMP1MMP7MMP9MMP8MMP13 | |
| Hydrochloric Acid SCHEMBL6989988 | 0.84 | MMP1 (0.39) | MMP1MMP7MMP9MMP8MMP13 | |
| SCHEMBL2606738 | 0.81 | TYR (0.47) | MMP1MMP7MMP9MMP8MMP13 | |
| SCHEMBL15578471 | 0.80 | MMP1 (0.39) | MMP1MMP7MMP9MMP8MMP13 | |
| SCHEMBL30310977 | 0.80 | TYR (0.42) | MMP1MMP7MMP9MMP8MMP13 | |
| SCHEMBL7546323 | 0.77 | MMP1 (0.37) | MMP1MMP7MMP9MMP8MMP13 | |
| SCHEMBL20026452 | 0.77 | KDM4E (0.47) | MMP1MMP7MMP9MMP8MMP13 | |
| Hydrochloric Acid SCHEMBL6992670 | 0.76 | MMP1 (0.36) | MMP1MMP7MMP9MMP8MMP13 | |
| SCHEMBL2118852 | 0.76 | MMP1 (0.36) | MMP1MMP7MMP9MMP8MMP13 | |
| SCHEMBL12249884 | 0.75 | MMP1 (0.36) | MMP1MMP7MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008154705-A1 | TRANSDERMAL DELIVERY OF ACTIVE AGENTS | APOLLO LIFE SCIENCES LIMITED (AU) | 2008-12-24 | — | — | WO | disclosed |
| EP-1978997-A1 | TRANSDERMAL DELIVERY OF PHARMACEUTICAL AGENTS | Apollo Life Sciences Limited (AU) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007070983-A1 | TRANSDERMAL DELIVERY OF PHARMACEUTICAL AGENTS | APOLLO LIFE SCIENCES LIMITED (AU) | 2007-06-28 | — | — | WO | disclosed |