Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27541825 | 0.77 | PPARA (0.50) | PPARGPPARAPPARDMMEACE | |
| SCHEMBL7804863 | 0.75 | KDM4E (0.39) | L3MBTL1LMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL28765229 | 0.74 | POLB (0.46) | PPARGPPARAMAPTCYP2C9CYP3A4 | |
| SCHEMBL28851016 | 0.74 | PSMB5 (0.54) | PPARGPPARAPPARDCYP2C9PSMB5 | |
| SCHEMBL28851015 | 0.74 | PSMB5 (0.54) | PPARGPPARAPPARDCYP2C9PSMB5 | |
| SCHEMBL27566624 | 0.73 | MME (0.45) | PPARGMMEACECPA1ACE2 | |
| SCHEMBL3369237 | 0.73 | PPARA (0.54) | PPARGPPARAPPARDL3MBTL1LMNA | |
| SCHEMBL7191581 | 0.72 | PPARA (0.73) | PPARGPPARAPPARDL3MBTL1LMNA | |
| SCHEMBL5364064 | 0.72 | PPARA (0.73) | PPARGPPARAPPARDL3MBTL1LMNA | |
| SCHEMBL8496632 | 0.72 | PSMB5 (0.55) | L3MBTL1MAPTPSMB5CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010238-A2 | ANTIDIABETIC AZABICYCLO [3. 1. 0] HEXAN COMPOUNDS | LUPIN LIMITED (IN) | 2008-01-24 | — | — | WO | disclosed |