Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 2/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4756880 | 0.89 | GRM4 (0.45) | STAT3MEN1KMT2ANPC1RAB9A | |
| SCHEMBL19978237 | 0.85 | ALDH1A1 (0.54) | MEN1KMT2ANPC1RAB9AGRM4 | |
| SCHEMBL4756409 | 0.84 | ALDH1A1 (0.57) | STAT3MEN1KMT2ANPC1RAB9A | |
| SCHEMBL31426452 | 0.82 | STAT3 (0.58) | STAT3MEN1KMT2ANPC1RAB9A | |
| SCHEMBL704075 | 0.82 | STAT3 (0.58) | STAT3MEN1KMT2ANPC1RAB9A | |
| SCHEMBL4757140 | 0.81 | GRM4 (0.45) | STAT3MEN1KMT2ANPC1RAB9A | |
| SCHEMBL4756451 | 0.76 | CCNE1 (0.52) | STAT3MEN1KMT2ANPC1RAB9A | |
| SCHEMBL4756532 | 0.75 | STAT3 (0.60) | STAT3MEN1KMT2ANPC1RAB9A | |
| SCHEMBL16918852 | 0.75 | GRM4 (0.42) | STAT3MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2696756 | 0.75 | STAT3 (0.53) | STAT3MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9820975-B2 | Compounds and methods for treating influenza | ROMARK LABORATORIES L.C. (US) | 2017-11-21 | — | — | US | disclosed |
| US-9820975-B2 | Compounds and methods for treating influenza | ROMARK LABORATORIES L.C. (US) | 2017-11-21 | — | — | US | disclosed |
| US-20160228415-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | ROMARK LABORATORIES L.C. (US) | 2016-08-11 | — | — | US | disclosed |
| US-9345690-B2 | Compounds and methods for treating influenza | ROMARK LABORATORIES L.C. (US) | 2016-05-24 | — | — | US | disclosed |
| US-20150250768-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | ROMARK LABORATORIES L.C. (US) | 2015-09-10 | — | — | US | disclosed |
| US-8895752-B2 | Alkylsulfonyl-substituted thiazolide compounds | ROMARK LABORATORIES L.C. (US) | 2014-11-25 | — | — | US | disclosed |
| US-20120122939-A1 | ALKYLSULFONYL-SUBSTITUTED THIAZOLIDE COMPOUNDS | ROMARK LABORATORIES, L.C. | 2012-05-17 | — | — | US | disclosed |
| US-8124632-B2 | Alkylsulfonyl-substituted thiazolide compounds | ROMARK LABORATORIES, L.C. (US) | 2012-02-28 | — | — | US | disclosed |
| US-20090036467-A1 | ALKYLSULFONYL-SUBSTITUTED THIAZOLIDE COMPOUNDS | ROMARK LABORATORIES L.C. | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150250768-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | HIF1AN, HAVCR2, NEU1 | STAT3 2441/4885MEN1 3237/4885KMT2A 2029/4885 |
| US-20160228415-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | HIF1AN, HAVCR2, NEU1 | STAT3 2441/4885MEN1 3237/4885KMT2A 2029/4885 |
| US-20120122939-A1 | ALKYLSULFONYL-SUBSTITUTED THIAZOLIDE COMPOUNDS | HAVCR2, EIF2AK2, AADAC | STAT3 63/4885MEN1 4564/4885KMT2A 2303/4885 |
| US-20090036467-A1 | ALKYLSULFONYL-SUBSTITUTED THIAZOLIDE COMPOUNDS | HAVCR2, EIF2AK2, AADAC | STAT3 63/4885MEN1 4564/4885KMT2A 2303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.