Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 11/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CALML3 | P27482 | 3/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12956266 | 0.87 | MAOA (0.43) | MAOAMAOBCALML3 | |
| SCHEMBL1031531 | 0.87 | MAOA (0.46) | MAOAMAOBCALML3 | |
| SCHEMBL1031535 | 0.87 | MAOA (0.46) | MAOAMAOBCALML3 | |
| SCHEMBL4743527 | 0.87 | MAOA (0.36) | MAOAMAOBCALML3 | |
| SCHEMBL13180781 | 0.86 | MAOA (0.40) | MAOAMAOBCALML3 | |
| SCHEMBL13180818 | 0.86 | MAOA (0.40) | MAOAMAOBCALML3 | |
| SCHEMBL1035631 | 0.85 | MAOA (0.46) | MAOAMAOBCALML3 | |
| SCHEMBL13180816 | 0.85 | MAOA (0.55) | MAOA | |
| SCHEMBL3080157 | 0.83 | MAOA (0.45) | MAOAMAOBCALML3 | |
| SCHEMBL17749419 | 0.81 | CALML3 (0.41) | MAOAMAOBCALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904489-A2 | PROCESS FOR THE SYNTHESIS OF TRIAZOLES | Rib-X Pharmaceuticals, Inc. (US) | 2008-04-02 | — | — | EP | disclosed |
| WO-2006133397-A2 | PROCESS FOR THE SYNTHESIS OF TRIAZOLES | RIB-X PHARMACEUTICALS, INC. (US) | 2006-12-14 | — | — | WO | disclosed |