Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4756438 | 1.00 | PDE2A (0.32) | PDE2ACTSKTAS1R3TAS1R1 | |
| SCHEMBL4756776 | 1.00 | PDE2A (0.32) | PDE2ACTSKTAS1R3TAS1R1 | |
| SCHEMBL4754048 | 0.95 | BRD4 (0.30) | — | |
| SCHEMBL3465608 | 0.91 | PDE2A (0.35) | PDE2ACTSKTAS1R3TAS1R1 | |
| SCHEMBL3465851 | 0.83 | — | — | |
| SCHEMBL4756458 | 0.83 | — | — | |
| SCHEMBL4757234 | 0.83 | — | — | |
| SCHEMBL3772837 | 0.79 | CAPN1 (0.34) | CTSK | |
| SCHEMBL8251805 | 0.78 | REN (0.35) | — | |
| SCHEMBL9907042 | 0.78 | REN (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1911762-A1 | Amino alcohols and their use as renin inhibitors | Speedel Experimenta AG (CH) | 2008-04-16 | — | — | EP | disclosed |