Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.50 |
| ▸ | F10 | P00742 | 17/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 3/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.46 |
| ▸ | PLAT | P00750 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24322499 | 1.00 | DPP4 (0.50) | DPP4F10GAAKMT2AF2 | |
| SCHEMBL3172775 | 1.00 | DPP4 (0.50) | DPP4F10GAAKMT2AF2 | |
| Hydrochloric Acid SCHEMBL3166514 | 0.99 | DPP4 (0.49) | DPP4F10GAAKMT2AF2 | |
| Hydrochloric Acid SCHEMBL3166507 | 0.99 | DPP4 (0.49) | DPP4F10GAAKMT2AF2 | |
| SCHEMBL24322865 | 0.87 | DPP4 (0.54) | DPP4F10GAA | |
| SCHEMBL5144938 | 0.85 | DPP4 (0.53) | DPP4F10GAA | |
| SCHEMBL6030098 | 0.85 | DPP4 (0.53) | DPP4F10GAA | |
| SCHEMBL5141746 | 0.85 | DPP4 (0.53) | DPP4F10GAA | |
| SCHEMBL6031441 | 0.85 | DPP4 (0.53) | DPP4F10GAA | |
| Hydrochloric Acid SCHEMBL4702354 | 0.85 | ALDH1A1 (0.48) | DPP4F10GAAKMT2AF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567489-B1 | PYRROLIDIN-2-ONE DERIVATIVES AS INHIBITORS OF THROMBIN AND FACTOR XA | GLAXO GROUP LTD (GB) | 2008-07-23 | — | — | EP | disclosed |