Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 5/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 2/20 | 0.38 |
| ▸ | PLAT | P00750 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10114188 | 0.81 | RAB9A (0.51) | P2RX1P2RX4P2RX7TMPRSS4GRM4 | |
| SCHEMBL4757405 | 0.72 | MEN1 (0.46) | P2RX1P2RX4P2RX7TMPRSS4GRM4 | |
| SCHEMBL4756660 | 0.67 | RAB9A (0.48) | GRM4MAPTKMT2AMEN1NPC1 | |
| SCHEMBL4757410 | 0.67 | NPC1 (0.42) | P2RX1P2RX7GRM4MAPTKMT2A | |
| SCHEMBL13524032 | 0.66 | CCNE1 (0.50) | P2RX1P2RX4P2RX7TMPRSS4KLKB1 | |
| SCHEMBL17422731 | 0.66 | RAB9A (0.57) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL4756712 | 0.65 | GRM4 (0.39) | GRM4MAPTKMT2ARXFP1ALDH1A1 | |
| SCHEMBL4756594 | 0.64 | MEN1 (0.45) | GRM4KLKB1KDRMAPTKMT2A | |
| SCHEMBL21246831 | 0.64 | POLB (0.54) | P2RX1P2RX4P2RX7TMPRSS4KLKB1 | |
| SCHEMBL5852388 | 0.62 | KLKB1 (0.72) | P2RX1P2RX4P2RX7TMPRSS4KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895752-B2 | Alkylsulfonyl-substituted thiazolide compounds | ROMARK LABORATORIES L.C. (US) | 2014-11-25 | — | — | US | disclosed |
| US-20120122939-A1 | ALKYLSULFONYL-SUBSTITUTED THIAZOLIDE COMPOUNDS | ROMARK LABORATORIES, L.C. | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122939-A1 | ALKYLSULFONYL-SUBSTITUTED THIAZOLIDE COMPOUNDS | HAVCR2, EIF2AK2, AADAC | P2RX1 4408/4885P2RX4 4261/4885P2RX7 3830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.