Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4756918 | 1.00 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1CASP3SENP7 | |
| SCHEMBL2433264 | 0.86 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1CASP3SENP7 | |
| SCHEMBL2433269 | 0.86 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1CASP3SENP7 | |
| SCHEMBL4161170 | 0.84 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1CASP3SENP7 | |
| SCHEMBL4161165 | 0.84 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1CASP3SENP7 | |
| SCHEMBL2432527 | 0.83 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1CASP3SENP7 | |
| SCHEMBL669399 | 0.83 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1CASP3SENP7 | |
| SCHEMBL2436135 | 0.82 | CYP2E1 (0.35) | ALDH1A1HTTKDM4E | |
| SCHEMBL2436133 | 0.82 | CYP2E1 (0.35) | ALDH1A1HTTKDM4E | |
| SCHEMBL14290921 | 0.81 | KMT2A (0.41) | ALDH1A1KMT2AMEN1CASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009000818-A1 | 3-CARBONYLAMINOTHIOPHENE-2-CARBOXYLIC ACIDS AS HEPATITIS C VIRUS INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-12-31 | — | — | WO | disclosed |
| WO-2009000818-A1 | 3-CARBONYLAMINOTHIOPHENE-2-CARBOXYLIC ACIDS AS HEPATITIS C VIRUS INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-12-31 | — | — | WO | disclosed |