SCHEMBL4757053

SCHEMBL4757053

C=CC(=CCCC)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.40
GRIK2 Q13002 1/20 0.40
EP300 Q09472 1/20 0.38
TSHR P16473 5/20 0.37
ALDH1A1 P00352 4/20 0.37
HPGD P15428 1/20 0.33
LMNA P02545 1/20 0.33
ZDHHC20 Q5W0Z9 1/20 0.31
ZDHHC2 Q9UIJ5 1/20 0.31
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10683497 0.87 EP300 (0.48) GRIK1EP300TSHRALDH1A1HPGD
SCHEMBL6561246 0.84 EP300 (0.60) EP300TSHRLMNAZDHHC20ZDHHC2
SCHEMBL6561250 0.84 EP300 (0.60) EP300TSHRLMNAZDHHC20ZDHHC2
SCHEMBL4584137 0.81
SCHEMBL1446836 0.81
SCHEMBL3431208 0.79 GRIK1 (0.36) GRIK1GRIK2EP300TSHR
SCHEMBL7123435 0.77 GRIK1 (0.37) GRIK1GRIK2EP300
SCHEMBL14600501 0.77 TSHR (0.33) GRIK1GRIK2TSHRALDH1A1HPGD
Acrylic Acid SCHEMBL9157484 0.76 LMNA (0.43) GRIK1GRIK2EP300TSHRALDH1A1
SCHEMBL27343701 0.76 GRIK1 (0.39) GRIK1GRIK2EP300

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050089600-A1 Chewing gum having extended flavor duration and methods for making same WM. WRIGLEY JR. COMPANY 2005-04-28 US claimed
CN-115023211-A Hair styling composition 株式会社漫丹 2022-09-06 CN disclosed
EP-2003983-B1 LONG-DURATION ENCAPSULATED FLAVORS AND CHEWING GUM USING SAME WRIGLEY W M JUN CO (US) 2013-01-23 EP disclosed
EP-2003983-A2 LONG-DURATION ENCAPSULATED FLAVORS AND CHEWING GUM USING SAME WM. WRIGLEY JR. COMPANY (US) 2008-12-24 EP disclosed
WO-2007117870-A2 LONG-DURATION ENCAPSULATED FLAVORS AND CHEWING GUM USING SAME WM. WRIGLEY JR. COMPANY (US) 2007-10-18 WO disclosed
US-20070231424-A1 LONG-DURATION ENCAPSULATED FLAVORS AND CHEWING GUM USING SAME WM. WRIGLEY JR. COMPANY 2007-10-04 US disclosed
EP-1137343-A4 CHEWING GUM HAVING EXTENDED FLAVOR DURATION AND METHODS FOR MAKING SAME WRIGLEY W M JUN CO (US) 2005-09-21 EP disclosed
US-20050089600-A1 Chewing gum having extended flavor duration and methods for making same WM. WRIGLEY JR. COMPANY 2005-04-28 US disclosed
EP-1137343-A1 CHEWING GUM HAVING EXTENDED FLAVOR DURATION AND METHODS FOR MAKING SAME WM. WRIGLEY JR. COMPANY (US) 2001-10-04 EP disclosed
WO-2000033664-A1 CHEWING GUM HAVING EXTENDED FLAVOR DURATION AND METHODS FOR MAKING SAME WM. WRIGLEY JR. COMPANY (US) 2000-06-15 WO disclosed