Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 16/20 | 0.65 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754302 | 1.00 | HSD11B1 (0.65) | HSD11B1NPY5RCYP2D6 | |
| SCHEMBL6080148 | 0.86 | HSD11B1 (0.54) | HSD11B1NPY5RCYP2D6 | |
| SCHEMBL4759179 | 0.85 | NPY5R (0.53) | HSD11B1NPY5RCYP2D6 | |
| SCHEMBL4757523 | 0.85 | NPY5R (0.53) | HSD11B1NPY5RCYP2D6 | |
| SCHEMBL6080897 | 0.84 | HSD11B1 (0.61) | HSD11B1NPY5RCYP2D6 | |
| SCHEMBL6080875 | 0.84 | HSD11B1 (0.61) | HSD11B1NPY5RCYP2D6 | |
| SCHEMBL6080425 | 0.83 | HSD11B1 (0.52) | HSD11B1NPY5RCYP2D6 | |
| SCHEMBL4758065 | 0.82 | HSD11B1 (0.51) | HSD11B1NPY5RCYP2D6 | |
| SCHEMBL4758063 | 0.82 | HSD11B1 (0.51) | HSD11B1NPY5RCYP2D6 | |
| SCHEMBL4758782 | 0.82 | HSD11B1 (0.48) | HSD11B1NPY5RCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758582-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2008-01-09 | — | — | EP | claimed |
| EP-1758582-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-03-07 | — | — | EP | claimed |
| WO-2006002349-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-01-05 | — | — | WO | claimed |