Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | CALML3 | P27482 | 1/20 | 0.33 |
| ▸ | SDHA | P31040 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4757118 | 0.92 | MAOA (0.52) | MAOAMAOBGRIN1GRIN2BLMNA | |
| SCHEMBL4758473 | 0.88 | MAOA (0.64) | MAOALRRK2MAOBLMNAPTGS1 | |
| SCHEMBL13515460 | 0.85 | MAOA (0.57) | MAOAMAOBGRIN1GRIN2BLMNA | |
| SCHEMBL13855705 | 0.81 | MAOA (0.53) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL4240451 | 0.81 | MAOA (0.53) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL3042118 | 0.81 | MAOA (0.55) | MAOAMAOBGRIN1GRIN2BLMNA | |
| SCHEMBL3029035 | 0.80 | MAOA (0.76) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL4758477 | 0.80 | MAOA (0.65) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL3028973 | 0.79 | MAOA (0.58) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL3033057 | 0.79 | MAOA (0.53) | MAOAMAOBGRIN1GRIN2BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902048-A1 | OXAZOLIDINONE CARBOXAMIDES CONTAINING AZETIDINE AND CYCLOBUTANE AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2008-03-26 | — | — | EP | claimed |
| WO-2007004037-A1 | OXAZOLIDINONE CARBOXAMIDES CONTAINING AZETIDINE AND CYCLOBUTANE AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2007-01-11 | — | — | WO | claimed |
| EP-1902026-A2 | TETRAHYDROCARBAZOLE DERIVATIVES USEFUL AS ANDROGEN RECEPTOR MODULATORS (SARM) | ELI LILLY AND COMPANY (US) | 2008-03-26 | — | — | EP | disclosed |
| WO-2007002181-A2 | TETRAHYDROCARBAZOLE DERIVATIVES USEFUL AS ANDROGEN RECEPTOR MODULATORS (SARM) | ELI LILLY AND COMPANY (US) | 2007-01-04 | — | — | WO | disclosed |