SCHEMBL4757133

SCHEMBL4757133

CCCOOC(=O)OC(=O)O

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
ALDH1A1 P00352 1/20 0.32
SOAT1 P35610 1/20 0.32
LMNA P02545 1/20 0.31
NAAA Q02083 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4757130 0.88 SOAT1 (0.42) FFAR3HCAR2ALDH1A1SOAT1LMNA
SCHEMBL180402 0.87 HCAR2 (0.31) FFAR3HCAR2ALDH1A1SOAT1
SCHEMBL5560623 0.83 ALDH1A1 (0.36) FFAR3HCAR2ALDH1A1SOAT1LMNA
SCHEMBL4776902 0.80 ALDH1A1 (0.35) HCAR2ALDH1A1SOAT1LMNANAAA
SCHEMBL28439909 0.80
SCHEMBL22720131 0.80 FFAR3 (0.40) FFAR3HCAR2ALDH1A1SOAT1LMNA
SCHEMBL216357 0.80 SOAT1 (0.46) HCAR2ALDH1A1SOAT1LMNANAAA
SCHEMBL11770603 0.78 SOAT1 (0.62) HCAR2ALDH1A1SOAT1LMNANAAA
SCHEMBL2497152 0.76 SOAT1 (0.46) FFAR3HCAR2ALDH1A1SOAT1LMNA
SCHEMBL193251 0.76 HCAR2 (0.40) HCAR2ALDH1A1SOAT1LMNANAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8920796-B2 Adsorbent for oral administration, and agent for treating or preventing renal or liver disease KUREHA CORPORATION (JP) 2014-12-30 US disclosed
US-8865161-B2 Adsorbent for an oral administration, and agent for treating or preventing renal or liver disease KUREHA CORPORATION (JP) 2014-10-21 US disclosed
US-8440228-B2 Adsorbent for an oral administration, and agent for treating or preventing renal or liver disease KUREHA CORPORATION (JP) 2013-05-14 US disclosed
US-20120244195-A1 ADSORBENT FOR AN ORAL ADMINISTRATION, AND AGENT FOR TREATING OR PREVENTING RENAL OR LIVER DISEASE KUREHA CORPORATION (JP) 2012-09-27 US disclosed
US-20080081073-A1 Surface treated and oxidized spherical activated carbon prepared from crosslinked vinyl resin, ion-exchange resin, or pitch; adsorbs large amount of toxins during retention period in an intestine; reduction of urinary protein excretion KUREHA CORPORATION (JP) 2008-04-03 US disclosed
EP-1525886-B1 Absorbent for oral administration, and agent for treating or preventing renal or liver disease KUREHA CORP (JP) 2008-03-12 EP disclosed
US-20080044477-A1 Adsorbent for an Oral Administration, and Agent for Treating or Preventing Renal or Liver Disease KUREHA CORPORATION (JP) 2008-02-21 US disclosed
US-20080031972-A1 Process For Manufacturing Spherical Activated Carbon KUREHA CORPORATION (JP) 2008-02-07 US disclosed
EP-1748031-A1 METHOD FOR PRODUCING SPHERICAL ACTIVATED CARBON Kureha Corporation (JP) 2007-01-31 EP disclosed
EP-1745793-A1 ADSORBENT FOR ORAL ADMINISTRATION, THERAPEUTIC OR PREVENTIVE AGENT FOR KIDNEY DISEASE, AND THERAPEUTIC OR PREVENTIVE AGENT FOR LIVER DISEASE Kureha Corporation (JP) 2007-01-24 EP disclosed
EP-1745792-A1 ADSORBENT FOR ORAL ADMINISTRATION, PREVENTIVE OR REMEDY FOR KIDNEY DISEASE AND PREVENTIVE OR REMEDY FOR LIVER DISEASE Kureha Corporation (JP) 2007-01-24 EP disclosed
US-20050112114-A1 Surface treated active carbon; controlling particle sizes, porosity KUREHA CHEMICAL INDUSTRY CO., LTD. 2005-05-26 US disclosed
EP-1525886-A1 Absorbent for oral administration, and agent for treating or preventing renal or liver disease Kureha Chemical Industry Co., Ltd. (JP) 2005-04-27 EP disclosed