Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | CXCR4 | P61073 | 11/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | CCR2 | P41597 | 1/20 | 0.47 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | TYK2 | P29597 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27861921 | 0.98 | CXCR4 (0.49) | PPARDCXCR4MEN1CHRM2CHRM1 | |
| SCHEMBL21607905 | 0.91 | PPARD (0.47) | PPARDCXCR4MEN1CHRM2CHRM1 | |
| Tert-Butyl Formate SCHEMBL27844698 | 0.87 | PPARD (0.53) | PPARDCXCR4MEN1CHRM2CHRM1 | |
| SCHEMBL20224126 | 0.85 | CXCR4 (0.49) | PPARDCXCR4MEN1CHRM2CHRM1 | |
| SCHEMBL28191749 | 0.84 | ALDH1A1 (0.58) | PPARDHRH3JAK2JAK1TYK2 | |
| SCHEMBL22642370 | 0.82 | PARP1 (0.46) | PPARDCXCR4MEN1CHRM2CHRM1 | |
| SCHEMBL25145683 | 0.82 | PPARD (0.45) | PPARDMEN1KMT2AJAK2JAK1 | |
| SCHEMBL18389831 | 0.82 | PPARD (0.55) | PPARDJAK2JAK1TYK2JAK3 | |
| SCHEMBL20382071 | 0.82 | PPARD (0.55) | PPARDMEN1KMT2AJAK2JAK1 | |
| SCHEMBL22642373 | 0.80 | HRH3 (0.48) | CXCR4MEN1CHRM2CHRM1ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020012424-A1 | SUBSTITUTED (AZA)INDOLE DERIVATIVES | RICHTER GEDEON NYRT. (HU) | 2020-01-16 | — | — | WO | disclosed |
| WO-2012019430-A1 | PHTHALAZINONE DERIVATIVE, AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | 上海恒瑞医药有限公司 (CN) | 2012-02-16 | — | — | WO | disclosed |
| WO-2009001021-A1 | IMIDAZOPYRIDINE DERIVATIVES USEFUL AS ENZYME INHIBITORS FOR THE TREATMENT OF CELL PROLIFERATIVE AND AUTOIMMUNE DISEASES | CHROMA THERAPEUTICS LTD. (GB) | 2008-12-31 | — | — | WO | disclosed |