Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6554359 | 0.84 | KMT2A (0.54) | KMT2ACA1CA2CA12CA4 | |
| SCHEMBL28126486 | 0.83 | KMT2A (0.56) | KMT2ACA1CA2CA12CA4 | |
| SCHEMBL516163 | 0.83 | KMT2A (0.60) | KMT2ACA1CA2CA12CA4 | |
| SCHEMBL11043667 | 0.80 | CA1 (0.62) | KMT2ACA1CA2CA12CA4 | |
| SCHEMBL6256715 | 0.80 | KMT2A (0.53) | KMT2ACA1CA2CA12CA4 | |
| SCHEMBL16991809 | 0.79 | CYP1A2 (0.46) | KMT2ACYP1A2LMNATSHRTP53 | |
| Phosphoric Acid SCHEMBL16816947 | 0.79 | KMT2A (0.56) | KMT2ACA1CA2CA12CA4 | |
| SCHEMBL9499182 | 0.79 | CYP1A2 (0.54) | KMT2ACA1CA2CA12CA4 | |
| SCHEMBL31433095 | 0.78 | CA1 (0.65) | KMT2ACA1CA2CA12CA4 | |
| SCHEMBL1592406 | 0.78 | CA1 (0.65) | KMT2ACA1CA2CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008047388-A2 | IMPROVED PROCESS FOR THE PREPARATION OF RANOLAZINE | IND-SWIFT LABORATORIES LIMITED (IN) | 2008-04-24 | — | — | WO | disclosed |