Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10723950 | 0.81 | KMT2A (0.46) | KMT2ACA1CA2CA12CA4 | |
| SCHEMBL4071169 | 0.81 | ALOX15 (0.44) | KMT2ALMNACYP1A2ADRA2BTP53 | |
| SCHEMBL11722029 | 0.80 | ALOX15 (0.47) | KMT2ACYP1A2ALDH1A1ADRA2BTDP1 | |
| SCHEMBL28126486 | 0.80 | KMT2A (0.56) | KMT2ACA1CA2CA12CA4 | |
| SCHEMBL4757451 | 0.80 | KMT2A (0.56) | KMT2ACA1CA2CA12CA4 | |
| Hydrochloric Acid SCHEMBL11409980 | 0.80 | KMT2A (0.45) | KMT2ACA1CA2CA12CA4 | |
| SCHEMBL2008418 | 0.79 | CA1 (0.59) | KMT2ACA1CA2CA12CA4 | |
| SCHEMBL516163 | 0.79 | KMT2A (0.60) | KMT2ACA1CA2CA12CA4 | |
| SCHEMBL4073503 | 0.79 | ADRA2A (0.42) | KMT2ALMNAALDH1A1ADRA2BTSHR | |
| SCHEMBL7913213 | 0.79 | ALDH1A1 (0.44) | KMT2ALMNACYP1A2ALDH1A1ADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005063699-A1 | N-ARYLOXYPROPANOLYL-N’-PHENETHYL-UREA | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2005-07-14 | — | — | WO | disclosed |